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Your doctor will probably tell you not to take metoclopramide. Archived from the original on 2011-09-22 . This new inside knowledge points to a high degree of manipulation by the government. Call your doctor if your symptoms do not improve, or if they get worse while using Prilosec. Decreased insulin production may occur in the pancreas due to a direct effect on pancreatic beta cells. Renal consequences of nonsteroidal antiinflammatory drugs".