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These may be symptoms of stomach or bowel bleeding. Apricus Biosciences, Inc. The serum concentration of Ondansetron can be increased when it is combined with Isavuconazole. Comparison of the intraocular pressure-lowering effect of latanoprost and timolol in patients with chronic angle closure glaucoma: a preliminary study". This older group of patients should be closely monitored during treatment with divalproex sodium for the development of acute liver injury with regular clinical assessments and serum liver test monitoring. The serum concentration of the active metabolites of Artesunate can be reduced when Artesunate is used in combination with Clotrimazole resulting in a loss in efficacy.