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William Andrew Publishing (22 October 2013). You should not take this medicine if you become pregnant or think you may be pregnant. The risk or severity of QTc prolongation can be increased when Ribociclib is combined with Erythromycin. Colchicine: Colchicine is a substrate for both CYP3A and the efflux transporter, P-glycoprotein (Pgp). Esomeprazole is also used to treat conditions in which the stomach produces too much acid such as Zollinger-Ellison syndrome. The metabolism of Remoxipride can be decreased when combined with Amiodarone.