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The metabolism of Debrisoquin can be decreased when combined with Venlafaxine. The second statistic comes from a 1999 study in the Journal of the American Medical Association, which found that 43 percent of the 1,749 women sampled (as opposed to 31 percent of men) had experienced some form of broadly-defined sexual dissatisfaction, including lack of desire and arousal, in the past two months. Patients should be questioned routinely about body changes related to lipoatrophy <>see Warnings and Precautions ( 5. A very bad form of prostate cancer was seen more often in some men taking drugs like this one than in those who were not. The metabolism of Ondansetron can be decreased when combined with Sertraline. After oral administration of 20 mg ACIPHEX, peak plasma concentrations (C max) of rabeprazole occur over a range of 2.