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Buspirone may increase the serotonergic activities of Alaproclate. Tapentadol may increase the central nervous system depressant (CNS depressant) activities of Prochlorperazine. While not typically recommended in heart failure, amlodipine may be used if other medications are not sufficient for high blood pressure or heart-related chest pain. The metabolism of Fluoxetine can be decreased when combined with Gemfibrozil. Hincll fragment containing the tet(M) gene from U. However, at times serious side effects can also occur.